Transfusion-Associated GVHD (TA-GVHD) has become a major concern in current transfusion practices for immuno-deficient and immuno-suppressed patients because of the associated high mortality rate. Immuno-suppressive therapies have not proven effective for TA-GVHD.
Because patient treatment of TA-GVHD is almost always ineffective, management must focus on prevention by minimizing the risk of developing the condition. Prevention has centered on reducing or inactivating transfused donor lymphocytes. The methods presently available in blood banks to physically remove T lymphocytes through washing or filtration do not provide effective prophyl-axis against TA-GVHD. Inactivation of transfused lymphocytes with the use of gamma irradiation of blood components remains the most efficient method for inhibiting lymphocyte blast transformation and mitotic activity, hence preventing TA-GVHD.
Safe to Use
- For use in any conventional hospital, clinic or laboratory environment.
- An advanced monitoring and control system tracks the irradiation process, confirming canister rotation, irradiation time and product position.
Easy to Operate
- A multi-line, menu driven display screen, with step-by-step instructions, will continue to operate for multiple cycles even in a power outage.
- Restricts access to the programming function with security passwords and key lock.
Barcode Reading Capabilities
- Can scan ISBT-128, Codabar and other blood labelling. Includes collection center, unit number, product code, blood type, collection and expiry dates.
- Various options for electronic record keeping of irradiated product data.
(Optional) Components for Research
- Optional components for research applications including test tube and animal holders.